Pair Name | Pterostilbene, Tamoxifen | ||
Phytochemical Name | Pterostilbene (PubChem CID: 5281727 ) | ||
Anticancer drug Name | Tamoxifen (PubChem CID: 2733526 ) | ||
Structure of Phytochemical |
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Structure of Anticancer Drug |
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Pair Name | Pterostilbene, Tamoxifen | |||
Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
Biological Phenomena | Induction-->Apoptosis | |||
In Vitro Model | MCF-7 | Invasive breast carcinoma of no special type | Homo sapiens (Human) | CVCL_0031 |
ZR-75-1 | Invasive breast carcinoma of no special type | Homo sapiens (Human) | CVCL_0588 | |
Result | Pterostilbene shows an additive inhibitory effect on breast cancer cells when combined with tamoxifen, most likely from augmented cancer cell apoptosis. |
No. | Title | Href |
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1 | Pterostilbene and tamoxifen show an additive effect against breast cancer in vitro. Am J Surg. 2010 Nov;200(5):577-80. doi: 10.1016/j.amjsurg.2010.07.022. | Click |